INHIBITION OF ENZYMES BY PHENYLMERCURY COMPOUNDS
نویسندگان
چکیده
منابع مشابه
INHIBITION OF ENZYMES BY PHENYLMERCURY COMPOUNDS* BY SISTER MARIE AUGUSTINE SMALT,t CORNELIUS W. KREKE,
Cytochrome oxidase and catalase are not regarded as sulfhydryldependent enzymes (1). The inhibition of the former by organic mercurial compounds (2) has been thought to involve denaturation (3) rather than interaction with sulfhydryl groups, and it has been suggested that the mercurial inhibition of catalase is also non-specific (4). Because the protein molecule contains reactive groups other t...
متن کاملThe inhibition of hydrolytic enzymes by organophosphorus compounds.
It has been shown that several hydrolytic enzymes with different specificities undergo similar reactions with diisopropyl phosphorofluoridate (1) and other related toxic organophosphorus compounds (2). These conclusions were based on kinetic studies, particularly the influence of pH on the rates of reaction, and on inhibition characteristics. Reactions of this type have provided a unique method...
متن کاملThe metabolism of phenylmercury by the rat.
The metabolism of [U-(14)C]phenylmercury acetate was studied in the rat. After a single subcutaneous dose a small proportion is excreted unchanged in urine, and a larger amount in bile with some resorption from the gut. The greater part of the dose is broken down in the tissues to yield inorganic mercury which is excreted mainly in faeces, and conjugates of phenol and quinol are excreted in uri...
متن کاملdetermination of alkylmercury compounds and phenylmercury in water and sediments by g.c.employing mocified westoo method
method previously employed by westoo for the determination of alkylmercury compounds was producing very wide picks during g.c. analyses. changing the column temperature, carrier gas flow and pressure did not supersede the problem. therefore change in packing materials was experienced. 5% dc-200 on gas-chrom did not work. a packing material used for chlorinated hydrocarbons w, 80-100 mesh. as th...
متن کاملThe inhibition of enzymes by beryllium.
1. The action of beryllium on the following enzymes has been examined: alkaline phosphatase (Escherichia coli and kidney), acid phosphatase, phosphoprotein phosphatase, apyrase (potato), adenosine triphosphatase (liver nuclei, liver mitochondria, brain microsomes), glucose 6-phosphatase, polysaccharide phosphorylases a and b, phosphoglucomutase, hexokinase, phosphoglyceromutase, ribonuclease, A...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1957
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)64991-9